Sarett oxidation
The Sarett oxidation is the oxidation of an alcohol to a ketone or an aldehyde using chromium trioxide and pyridine. Primary alcohols will only be oxidised to the aldehyde and not on to carboxylic acids.
The reagent is named after the American chemist Lewis Hastings Sarett (1917– 1999).
See also
References
- G. I. Poos, G. E. Arth, R. E. Beyler, and L. H. Sarett (1953). "Approaches to the Total Synthesis of Adrenal Steroids.1 V. 4b-Methyl-7- ethylenedioxy-1,2,3,4,4aα,4b,5,6,7,8,10,10a β-dodecahydrophenanthrene-4 β-ol-1-one and Related Tricyclic Derivatives". Journal of the American Chemical Society 75 (2): 422–429. doi:10.1021/ja01098a049.
- J. R. Holum, J. Org. Chem. 26, 4814 (1961)
- E. J. Kris, Chemistry & Industry (London) 1961 1834)
- V. I. Stenberg, and R. J. Perkins, J. Org. Chems. 28, 323 (1963)
- P. G. Gassman and P. G. Pape, J. Org. Chem. 29, 160 (1964).
External links